LINK-group

Summary: The ModuLand method-family

ModuLand logo

Background: Network communities help the functional organization and evolution of complex networks. However, the development of a method, which is both fast and accurate, provides modular overlaps and partitions of a heterogeneous network, has proven to be rather difficult.

Methodology/Principal Findings: Here we introduce the novel concept of ModuLand and its plug-in to the widely used Cytoscape progam, an integrative method family determining overlapping network modules as hills of an influence function-based, centrality-type community landscape, and including several widely used modularization methods as special cases. As various adaptations of the method family, we developed several algorithms, which provide an efficient analysis of weighted and directed networks, and (1) determine overlapping modules with high resolution; (2) uncover a detailed hierarchical network structure allowing an efficient, zoom-in analysis of large networks; (3) allow the determination of key network nodes and (4) help to predict network dynamics.

Conclusions/Significance: The concept opens a wide range of possibilities to develop new approaches and applications including network routing, classification, comparison and prediction.


Downloadable materials


ModuLand: Cytoscape plug-in containing the Linkland and ProportionalHill methods


ModuLand method: full package containing the NodeLand, LinkLand, Perturland, Edgeweight, ProportionalHill, GradientHill and Totalhill methods
Changes of version 1.3 (June 2012)

Contact us / keep updated

  • You can send us your comment using this contact form [link] or by sending an email to [email protected].
  • Send us a message either by using the contact form or by email with the subject "update" and we will keep you informed about future updates.

Successful applications of the ModuLand method

Now you are viewing the most recent version of this site. You can reach the earlier versions here:

Published by the LINK-Group | Editor: Péter Csermely | Last updated on 10 09 2013
Questions | Address | Design and maintenance | Visitors since 7th July 2004: website page counter