Csaba Pál


  • Nationality: Hungarian
  • Address: Theoretical Biology and Ecology Modelling Group.
    Hungarian Academy of Sciences and Department of Plant Taxonomy and Ecology, Eötvös Loránd University
    Pázmány Péter Sétány 1/C, H-1117, Budapest, HUNGARY
  • E-mail: pal [at]


  • 1994-1998 undergraduate student. Eötvös Loránd University. Budapest.
  • 1998 BA. Thesis: Evolution of epigenetic inheritance systems (in hungarian)
  • 1998 – 2001 graduate student. Eötvös Loránd University. Budapest. Supervisor: Eörs Szathmáry
  • 1999- 2000 Travel grant. University of Bath. UK. Supervisor: Laurence D.Hurst
  • 2000 – 2001 Junior Fellowship. Collegium Budapest. Hungary
  • 2001. PhD Thesis. Title: Sex and genome evolution
  • 2001-2002 Royal Society Postdoctoral Fellowship. University of Bath, UK
  • 2003 – Research Assistant. Theoretical Biology and Ecology Research Group. Hungarian Academy of Sciences and Eötvös University

Competitons, Honors and Awards

  • 2005 – Talentum Award of the Hungarian Academy of Science

Invited talks

  • 15.08.1999. V. Congress ofthe European Society for Evolutionary Biology. Barcelona. Title: The evolution of dual inheritance systems on the adaptive landscape.
  • 10.12.1999 Seminar talk. University of Sussex. UK. Title: Evolution of gene number.
  • 12. 4.2000 Brown bag discussion. Konrad Lorenz Institute. Altenberg, Austria. Title: Epigenetic inheritance in evolution.
  • 25.11.2001. Contextualizing the genome: The role of Epigenetics in Genetics, Development and Evolution. Ghent. Title: Mutational robustness and evolution.
  • 04.07.2004. Structural Approaches to Sequence Evolution: Molecules, Network, Populations. Interdisciplinary Conference on Molecular Evolution


  1. Pál, C. (1998). Plasticity, memory and the adaptive landscape of the genotype. Proc. Roy.Soc.London.B. 265: 1319-1323. IF: 3.4
  2. Pál, C. and Miklós, I. (1999) Epigenetic inheritance, genetic assimilation and speciation Jour.Theor.Biol.200: 16-37 IF:1.5
  3. Pál, C. and Szathmáry, E. (2000) The concept of fitness and individuality revisited. Jour.Evol.Biol. 13:348-357 IF: 2.6
  4. Williams, E Pál, C. and Hurst. L.D. (2000). Molecular evolution of signal peptides. Gene 253: 313-322 IF: 2.8
  5. Pál, C. and Hurst, L.D. (2000) The evolution of gene number: are heritable and non-heritable errors equally important? Heredity 84:393-400. IF: 1.6
  6. Pál, C. and Papp B. (2000). Selfish cells threaten multicellular life. Trends.Ecol.Evol. 15 :351-352. IF: 11.9
  7. Hurst, L.D. and Pál, C (2001): Evidence of purifying selection acting on silent sites in BRCA1. Trends Genet. 17: 62-65 IF: 13.2
  8. Pál, C. (2001) Yeast prions and evolvability. Trends. Genet. 17:167-9. IF: 13.2
  9. Szathmáry, E. Jordán, F. and Pál, C. (2001) Can genes explain biological complexity? Science. 292:1315-6. IF: 26.6
  10. Pál, C. Papp B. and Hurst, L.D. (2001): Highly expressed genes in yeast evolve slowly. Genetics 158: 927-931 IF:4.5
  11. Pál, C. Papp B. and Hurst, L.D. (2001): Does the recombination rate affect the efficiency of purifying selection? The yeast genome provides a partial answer.
    Mol Biol Evol. 18:2323-6. IF: 5.2
  12. Hurst LD, Williams EJ, Pal C (2002): Natural selection promotes the conservation of linkage of co-expressd genes . Trends Genet. 18:604-606. IF: 13.2
  13. Pál, C. Papp B. and Hurst, L.D. (2003): Genomic function: Rate of evolution and gene dispensability. Nature. 421:496-7. IF: 30.4
  14. Papp, B., Pál, C. and Hurst, L.D. (2003) Evolution of cis-regulatory elements in duplicated genes of yeast. Trends Genet. 19: 417-422 IF: 13.2
  15. Pál, C. and Hurst, L.D (2003): Evidence for co-evolution of gene order and recombination rate Nature Gen. 33:392-5 IF: 26.7
  16. Papp, B., Pál, C. and Hurst, L.D. (2003) Dosage sensitivity and the evolution of gene families in yeast. Nature 424: 194-7 IF: 30.4
  17. Hurst, L.D., Pál, C. and Lercher, M.J. (2004): The evolutionary dynamics of eukaryotic gene order. Nature Review Genetics 5, 299 –310 IF: 21.8
  18. Pál, C. and Hurst, L.D. (2004): Evidence against the selfish operon theory. Trends Genet. 20, 232-234. IF: 13.2
  19. Pál, C. and Hurst, L.D (2003): Epigenetic inheritance and evolutionary adaptation. In: Organelles, Genomes and Eukaryotic Phylogeny: an Evolutionary Synthesis in the Age of Genomics (e.d.)Hirt R. and Horner D. (in press)
  20. Papp, B., Pál, C. and Hurst, L.D. (2004) Metabolic network analysis of the causes and evolution of gene dispensability in yeast Nature 429, 661-664. IF: 30.4
  21. Soti, C., Pal, C., Papp, B. and Csermely, P. (2005) Molecular chaperones as regulatory elements of cellular networks. Curr. Opin. Cell Biol. 17, 210-215.
  22. Hurst, L.D. and Pal, C. (2005) Dissecting dispensability. Nature Genet. 37, 214-215.
  23. Pal, C., Papp, B. and Lercher, M.J. (2005) Adaptive evolution of bacterial metabolic networks by horizontal gene transfer. Nature Genet. 37, 1372-1375
  24. Pál, C., Papp, B., Lercher, M.J., Csermely, P., Oliver, S.G. and Hurst, L.D. (2006) Chance and necessity in the evolution of minimal metabolic networks. Nature, in press
Csaba Pál
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