Balázs Papp


  • Place and date of birth: Debrecen, 4th November, 1977
  • Nationality: Hungarian
  • Address: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Temesvári krt. 62, H-6701, Hungary
  • Web:
  • E-mail: pappb [at]


  • 2001 MS. University of Debrecen, Faculty of Science, Hungary (formerly Kossuth Lajos University), Diploma: biologist (geneticist), biology and physics teacher
    Advisors: Dr. Csaba Pál, Prof. Eörs Szathmáry and Dr. Katalin Pecsenye
  • 2001 - 2004 PhD student at the Department of Plant Taxonomy and Ecology, Eötvös University.
    Supervisor: Prof Eörs Szathmáry


  • 2002 Visiting scholar (Marie Curie Fellowship) for 6 months, University of Bath, Bath, UK. Worked with Professor Laurence D. Hurst.
  • 2003 Junior Fellow at the Collegium Budapest (Institute for Advanced Study) for 5 months.
  • 2004 Visiting scholar (Marie Curie Fellowship) for 6 months, University of Manchester, Manchester, UK. Worked with Professor Stephen G. Oliver.
  • 2005 – 2008 Long-Term Fellow of the Human Frontier Science Program Organisation, The University of Manchester, Manchester, UK and Biological Research Center, Szeged, Hungary.

Honors and Awards, scholarships

  • 2000 Scholarship of the Republic of Hungary
  • 2001 I. prize, National Conference for Student Scientists (Theoretical Biology)
  • 2001 Pro Scientia Medal
  • 2007 Junior Prima Prize (Hungary)

Talks, conferences

  • 2007 Integrative Post-Genomics ’07, Lyon, France (keynote speaker)
  • 2007 Otto Warburg International Summer School on Computational Systems Biology, Berlin, Germany
  • 2007 Population and Evolutionary Approaches to Biological Systems, Cambridge, UK
  • 2007 35th Annual Conference on Yeasts, Smolenice, Slovakia (plenary talk)
  • 2007 Phenomics Workshop, Göteborg, Sweeden
  • 2007 CIAR Genetic Networks Program, Toronto, Canada
  • 2006 Cell Signalling Systems Biology Meeting, Warnemünde, Germany (plenary talk)
  • 2006 “Integrated studies of genetic networks: A new evolutionary synthesis" Marathon, Florida Keys, US
  • 2004 XVI. Seminar Algorithmics and Biology (Genomes, Chromosomes, Cells and Developmental Evolution). Laboratoire de Biométrie et Biologie Évolutive, Université Claude Bernard, Lyon, France
  • 2004 Gordon Research Conference on „Macromolecular Organization & Cell Function”, Oxford, UK


Click here for an up-to-date list of publications

  1. Pinney, J.W., Papp, B., Hyland, C., Wambua, L., Westhead, D.R., McConkey, G.A. (2007) Metabolic reconstruction and analysis for parasite genomes. Trends Parasitol 23: 548-554.
  2. Fehér, T., Papp, B., Pál, C., Pósfai, G. (2007) Systematic Genome Reductions: Theoretical and Experimental Approaches. Chemical Reviews 107: 3498-3513.
  3. Miskey, C., Papp, B., Mates, L., Sinzelle, L., Keller, H., Izsvak, Z., Ivics, Z. (2007) The Ancient Mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends. Mol Cell Biol. 27: 4589-600.
  4. Bundy, J.G., Papp, B., Harmston, R., Browne, R.A., Clayson, E.M., Burton, N., Reece, R.J., Oliver, S.G., Brindle, K.M. (2007) Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling. Genome Res. 17: 510-19
  5. *Harrison, R., *Papp, B., Pál, C., Oliver, S.G., Delneri, D. (2007) Plasticity of genetic interactions in metabolic networks of yeast. Proc Natl Acad Sci U S A. 104: 2307-12.
  6. Sopko, R., Papp, B., Oliver, S.G. and Andrews, B.J. (2006) Phenotypic activation to discover biological pathways and kinase substrates. Cell Cycle 5:1397-402.
  7. Pál, C., Papp, B., Lercher, M.J., Csermely, P., Oliver, S.G. and Hurst, L.D. (2006) Chance and necessity in the evolution of minimal metabolic networks. Nature, in press
  8. Sopko, R., Huang, D., Preston, N., Chua, G., Papp, B., Kafadar, K., Snyder, M., Oliver, S.G., Cyert, M., Hughes, T.R., Boone, C. and Andrews, B. (2006) Mapping Pathways and Phenotypes by Systematic Gene Overexpression. Mol. Cell 21, 319-330.
  9. Papp, B. and Oliver, S. (2005) Genome-wide analysis of the context-dependence of regulatory networks. Genome Biol. 6, 206.
  10. Pal, C., Papp, B. and Lercher, M.J. (2005) Adaptive evolution of bacterial metabolic networks by horizontal gene transfer. Nature Genet. 37, 1372-1375
  11. Soti, C., Pal, C., Papp, B. and Csermely, P. (2005) Molecular chaperones as regulatory elements of cellular networks. Curr. Opin. Cell Biol. 17, 210-215.
  12. Papp, B., Pál, C. and Hurst, L.D. (2004) Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 429, 661-664.
  13. Papp, B., Pál, C. and Hurst, L.D. (2003) Evolution of cis-regulatory elements in duplicated genes of yeast. Trends Genet. 19: 417-22.
  14. Papp, B., Pál, C. and Hurst, L.D. (2003) Dosage sensitivity and the evolution of gene families in yeast. Nature 424: 194-7.
  15. Pál, C., Papp, B. and Hurst, L.D. (2003) Genomic function: Rate of evolution and gene dispensability. Nature 421:496-7.
  16. Pál, C. Papp B. and Hurst, L.D. (2001) Does the recombination rate affect the efficiency of purifying selection? The yeast genome provides a partial answer. Mol. Biol. Evol. 18:2323-6.
  17. Pál, C. Papp, B. and Hurst, L.D. (2001) Highly expressed genes in yeast evolve slowly. Genetics 158: 927-931.
  18. Pál, C. and Papp, B. (2000) Selfish cells threaten multicellular life. Trends Ecol. Evol. 15: 351-352.
Balázs Papp
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