Personal
- Place and date of birth: Debrecen, 4th November, 1977
- Nationality: Hungarian
- Address: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Temesvári krt. 62, H-6701, Hungary
- Web: www.brc.hu/sysbiol/bpapp.html
- E-mail: pappb [at] brc.hu
Education
- 2001 MS. University of Debrecen, Faculty of Science, Hungary (formerly Kossuth Lajos University), Diploma: biologist (geneticist), biology and physics teacher
Advisors: Dr. Csaba Pál, Prof. Eörs Szathmáry and Dr. Katalin Pecsenye
- 2001 - 2004 PhD student at the Department of Plant Taxonomy and Ecology, Eötvös University.
Supervisor: Prof Eörs Szathmáry
Fellowships
- 2002 Visiting scholar (Marie Curie Fellowship) for 6 months, University of Bath, Bath, UK. Worked with Professor Laurence D. Hurst.
- 2003 Junior Fellow at the Collegium Budapest (Institute for Advanced Study) for 5 months.
- 2004 Visiting scholar (Marie Curie Fellowship) for 6 months, University of Manchester, Manchester, UK. Worked with Professor Stephen G. Oliver.
- 2005 – 2008 Long-Term Fellow of the Human Frontier Science Program Organisation, The University of Manchester, Manchester, UK and Biological Research Center, Szeged, Hungary.
Honors and Awards, scholarships
- 2000 Scholarship of the Republic of Hungary
- 2001 I. prize, National Conference for Student Scientists (Theoretical Biology)
- 2001 Pro Scientia Medal
- 2007 Junior Prima Prize (Hungary)
Talks, conferences
- 2007 Integrative Post-Genomics ’07, Lyon, France (keynote speaker)
- 2007 Otto Warburg International Summer School on Computational Systems Biology, Berlin, Germany
- 2007 Population and Evolutionary Approaches to Biological Systems, Cambridge, UK
- 2007 35th Annual Conference on Yeasts, Smolenice, Slovakia (plenary talk)
- 2007 Phenomics Workshop, Göteborg, Sweeden
- 2007 CIAR Genetic Networks Program, Toronto, Canada
- 2006 Cell Signalling Systems Biology Meeting, Warnemünde, Germany (plenary talk)
- 2006 “Integrated studies of genetic networks: A new evolutionary synthesis" Marathon, Florida Keys, US
- 2004 XVI. Seminar Algorithmics and Biology (Genomes, Chromosomes, Cells and Developmental Evolution). Laboratoire de Biométrie et Biologie Évolutive, Université Claude Bernard, Lyon, France
- 2004 Gordon Research Conference on „Macromolecular Organization & Cell Function”, Oxford, UK
Publications
Click here for an up-to-date list of publications
- Pinney, J.W., Papp, B., Hyland, C., Wambua, L., Westhead, D.R., McConkey, G.A. (2007) Metabolic reconstruction and analysis for parasite genomes. Trends Parasitol 23: 548-554.
- Fehér, T., Papp, B., Pál, C., Pósfai, G. (2007) Systematic Genome Reductions: Theoretical and Experimental Approaches. Chemical Reviews 107: 3498-3513.
- Miskey, C., Papp, B., Mates, L., Sinzelle, L., Keller, H., Izsvak, Z., Ivics, Z. (2007) The Ancient Mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends. Mol Cell Biol. 27: 4589-600.
- Bundy, J.G., Papp, B., Harmston, R., Browne, R.A., Clayson, E.M., Burton, N., Reece, R.J., Oliver, S.G., Brindle, K.M. (2007) Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling. Genome Res. 17: 510-19
- *Harrison, R., *Papp, B., Pál, C., Oliver, S.G., Delneri, D. (2007) Plasticity of genetic interactions in metabolic networks of yeast. Proc Natl Acad Sci U S A. 104: 2307-12.
- Sopko, R., Papp, B., Oliver, S.G. and Andrews, B.J. (2006) Phenotypic activation to discover biological pathways and kinase substrates. Cell Cycle 5:1397-402.
- Pál, C., Papp, B., Lercher, M.J., Csermely, P., Oliver, S.G. and Hurst, L.D. (2006) Chance and necessity in the evolution of minimal metabolic networks. Nature, in press
- Sopko, R., Huang, D., Preston, N., Chua, G., Papp, B., Kafadar, K., Snyder, M., Oliver, S.G., Cyert, M., Hughes, T.R., Boone, C. and Andrews, B. (2006) Mapping Pathways and Phenotypes by Systematic Gene Overexpression. Mol. Cell 21, 319-330.
- Papp, B. and Oliver, S. (2005) Genome-wide analysis of the context-dependence of regulatory networks. Genome Biol. 6, 206.
- Pal, C., Papp, B. and Lercher, M.J. (2005) Adaptive evolution of bacterial metabolic networks by horizontal gene transfer. Nature Genet. 37, 1372-1375
- Soti, C., Pal, C., Papp, B. and Csermely, P. (2005) Molecular chaperones as regulatory elements of cellular networks. Curr. Opin. Cell Biol. 17, 210-215.
- Papp, B., Pál, C. and Hurst, L.D. (2004) Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 429, 661-664.
- Papp, B., Pál, C. and Hurst, L.D. (2003) Evolution of cis-regulatory elements in duplicated genes of yeast. Trends Genet. 19: 417-22.
- Papp, B., Pál, C. and Hurst, L.D. (2003) Dosage sensitivity and the evolution of gene families in yeast. Nature 424: 194-7.
- Pál, C., Papp, B. and Hurst, L.D. (2003) Genomic function: Rate of evolution and gene dispensability. Nature 421:496-7.
- Pál, C. Papp B. and Hurst, L.D. (2001) Does the recombination rate affect the efficiency of purifying selection? The yeast genome provides a partial answer. Mol. Biol. Evol. 18:2323-6.
- Pál, C. Papp, B. and Hurst, L.D. (2001) Highly expressed genes in yeast evolve slowly. Genetics 158: 927-931.
- Pál, C. and Papp, B. (2000) Selfish cells threaten multicellular life. Trends Ecol. Evol. 15: 351-352.